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Mike Evans, Christian Kirk Out for 49ers; DJ Moore, Keon Coleman Clear for Bills-Vikings MNF

Posted November 8, 2026 at 8:20 AM ET

Sunday’s slate opens with a genuine fantasy problem out west: San Francisco will play its late-afternoon home game against Las Vegas without Mike Evans, Christian Kirk and Deebo Samuel all unavailable at once, pushing Demarcus Robinson and Brandin Cooks into lead roles. There’s better news in Buffalo, where DJ Moore and Keon Coleman both cleared the Bills’ injury report ahead of Monday night’s trip to Minnesota, closing the book on the question we left open Saturday. Kyler Murray’s hamstring tag became official over the weekend, confirming Carson Wentz as Minnesota’s starter, and the Falcons placed Brian Robinson Jr. on injured reserve just days after acquiring him.

Status At a Glance

PlayerTeam / PosStatusFantasy Move
Mike EvansSF WRπŸ”΄ Out (Achilles tendinitis)Bench; start Demarcus Robinson or Brandin Cooks instead
Christian KirkSF WRπŸ”΄ IR (knee)Drop in shallow leagues; Robinson and Cooks absorb his routes
Deebo SamuelSF WRπŸ”΄ Out (hamstring)Bench; same target bump to Robinson and Cooks
Demarcus RobinsonSF WR🟒 Activated off IR, full practice Fri.Streamable flex with San Francisco’s top three receivers out
DJ MooreBUF WR🟒 Cleared, full practiceStart with normal confidence Monday night
Keon ColemanBUF WR🟒 Cleared, full practiceStart with normal confidence Monday night
Joshua PalmerBUF WRπŸ”΄ Out (hamstring)Bench; limited fantasy impact behind Moore, Shakir and Coleman
Jauan JenningsMIN WRπŸ”΄ Out (calf)Bench for Monday night; lean on Jefferson and Addison instead
Amon-Ra St. BrownDET WR🟑 Questionable (rib)Keep in lineups unless he is inactive at 11:30 AM ET; have a 4 PM WR ready
A.J. BrownNE WRπŸ”΄ Out (ankle/knee)Bench for Sunday’s home game vs. Green Bay
George PickensDAL WR🟑 Questionable (hamstring)Check 11:30 AM ET inactives; line up a late-window WR as a pivot
DeVonta SmithPHI WRπŸ”΄ Out (hamstring)Bench for Sunday’s home game vs. the Giants
Garrett WilsonNYJ WRπŸ”΄ Out (concussion)Bench for Sunday’s game at Kansas City
Kyler MurrayMIN QBπŸ”΄ Out (hamstring)Bench; Carson Wentz remains Minnesota’s starter
Brian Robinson Jr.ATL RBπŸ”΄ IR (hamstring)Drop; Bijan Robinson is unaffected as Atlanta’s lead back
Cam SkatteboNYG RBπŸ”΄ Doubtful (hamstring)Bench at Philadelphia; plan on playing without him

Our 🟒/🟑/πŸ”΄/βšͺ tiers are editorial availability-risk calls, not NFL designations: 🟒 trending toward playing Β· 🟑 availability uncertain Β· πŸ”΄ elevated risk of missing, or confirmed out Β· βšͺ bye. Questionable/Doubtful/Out labels appear only once a team’s final injury report has been released β€” true for the 49ers-Raiders and Bills-Vikings games as of this writing β€” and reflect Friday’s and Saturday’s team reports as cited below.

Wide Receivers

πŸ”΄ Out β€” Mike Evans (SF): Evans did not practice all week and was ruled out Friday for Sunday’s home game against Las Vegas, per NBC Sports. He’s been dealing with Achilles tendinitis that head coach Kyle Shanahan said dates back to San Francisco’s Week 6 win over Washington. Fantasy Action: Bench Evans; Demarcus Robinson and Brandin Cooks are the direct beneficiaries in San Francisco’s passing game.

πŸ”΄ IR β€” Christian Kirk (SF): Kirk was ruled out Friday after missing a second straight practice with a knee issue Shanahan described as a meniscus injury, and the 49ers placed him on injured reserve Saturday, per our injury tracker. Fantasy Action: Drop Kirk in shallow and medium leagues; he won’t be a factor for at least the next four games.

πŸ”΄ Out β€” Deebo Samuel (SF): Samuel continues to recover from a hamstring strain and did not practice this week, ruled out Friday for Sunday’s game, per 49ersWebZone. Fantasy Action: Bench Samuel; he joins Evans and Kirk on the sideline.

🟒 Activated β€” Demarcus Robinson (SF): With San Francisco’s top three receivers all out, Robinson’s activation off injured reserve looms large β€” he practiced fully Friday after his 21-day window opened and is listed as San Francisco’s left-side WR1 on the depth chart, per 49ersWebZone. Jordan Watkins and Brandin Cooks are next on the depth chart behind him. Fantasy Action: Start Robinson as a streamable flex and add Cooks if either is available in your league; both see a real snap and target bump against a Las Vegas defense that just lost a receiver-corps battle of attrition of its own.

🟒 Cleared β€” DJ Moore & Keon Coleman (BUF): Both wideouts practiced fully and carry no injury designation into Monday night’s game at Minnesota, resolving the questions we flagged Saturday morning, per Bills reporting. Buffalo’s only receiver ruled out is Joshua Palmer (hamstring), a depth piece with minimal standalone fantasy value. Fantasy Action: Start Moore and Coleman with normal confidence; no need to hedge either in Monday night lineups.

πŸ”΄ Out β€” Jauan Jennings (MIN): Jennings (calf) is out for Monday’s home game against Buffalo, confirmed on the Vikings’ injury report. Fantasy Action: Bench Jennings; Justin Jefferson and Jordan Addison absorb the target share, with Minnesota’s receiver room otherwise unaffected.

🟑 Questionable β€” Amon-Ra St. Brown (DET): St. Brown carries a questionable tag with a rib injury into Detroit’s 1:00 PM ET game at Miami, per the Lions’ final Week 9 injury report on NFL.com. He was not ruled out, so the decision comes with inactives about 90 minutes before kickoff. Fantasy Action: Keep him in your lineup, but have a 4:05 or 4:25 PM ET receiver on your bench in case he is inactive.

πŸ”΄ Out β€” A.J. Brown (NE): The Patriots ruled Brown out for Sunday’s 4:25 PM ET home game against Green Bay with an ankle/knee injury, per New England’s final injury report on NFL.com. Fantasy Action: Bench Brown in all formats this week.

🟑 Questionable β€” George Pickens (DAL): Pickens is questionable with a hamstring injury for Dallas’ 1:00 PM ET game at Indianapolis, per the Cowboys’ final injury report on NFL.com. Fantasy Action: Check the 11:30 AM ET inactives and keep a late-window receiver ready as a pivot.

πŸ”΄ Out β€” DeVonta Smith (PHI): Smith is out with a hamstring injury for Philadelphia’s 1:00 PM ET home game against the Giants, per the Eagles’ final injury report on NFL.com. Fantasy Action: Bench Smith this week.

πŸ”΄ Out β€” Garrett Wilson (NYJ): Wilson entered the concussion protocol on Nov. 4, per the Jets, and has been ruled out for Sunday’s 1:00 PM ET game at Kansas City, per the team’s final injury report on NFL.com. Fantasy Action: Bench Wilson this week.

Four more wideouts came off injured reserve this week and enter game day as questionable rather than full participants: Atlanta’s Beaux Collins (hip), Denver’s Pat Bryant, New Orleans’ Jordyn Tyson and New England’s Mack Hollins. None projects as more than a desperation deep-league add even if active.

Quarterbacks

πŸ”΄ Out β€” Kyler Murray (MIN): Murray’s hamstring tag became official over the weekend, locking in Carson Wentz as Minnesota’s starter for Monday night’s game against Buffalo β€” a move first reported Thursday and confirmed on the Vikings’ weekend report. Fantasy Action: Bench Murray in all single-QB formats; Wentz remains only a desperation streamer in superflex behind a full Minnesota offense.

Running Backs

πŸ”΄ IR β€” Brian Robinson Jr. (ATL): Robinson landed on injured reserve Saturday with a hamstring issue, just days after the Falcons acquired him. Bijan Robinson remains Atlanta’s unquestioned lead back, with Khalil Herbert the clear backup. Fantasy Action: Drop Robinson in redraft leagues; there’s no pathway to fantasy relevance behind Bijan.

πŸ”΄ Doubtful β€” Cam Skattebo (NYG): Skattebo is listed doubtful with a hamstring injury for the Giants’ 1:00 PM ET game at Philadelphia, per New York’s final injury report on NFL.com. Doubtful players rarely suit up. Fantasy Action: Bench Skattebo and plan on playing without him this week.

For every replacement option and streamer at each position, see the full Week 9 injury report, updated live throughout the day.

Sources

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